For many years, a Los Angeles psychoanalyst to the stars named Milton Wexler led the fight against Huntington’s disease, a rare and fatal congenital illness. His Hereditary Disease Foundation didn’t have much money, so he attracted scientists to his cause by inviting them to parties where they could mingle with his celebrity friends.
In 1997 a single donor began charting a new direction for the research effort into Huntington’s. He poured millions and eventually hundreds of millions of dollars into an aggressive search for a cure. At first he worked with Wexler’s organization, then split off and established his own network of nonprofit foundations.
via Three Mysterious Philanthropists Fund Fourth-Largest U.S. Charity – Businessweek.